Premier League Predictions: Gameweek 6

The Premier League's big six teams have advanced to the Carabao Cup fourth round, with Manchester United's chaotic 2-1 victory over Chelsea contrasting with the smoother progress of other clubs. The schedule remains packed, including a Monday night Premier League match, ensuring no respite for teams or viewers in Gameweek 6.

Manchester United, buoyed by their midweek win, face Brentford in an early kick-off. Despite suffering heavy defeats at Brentford in recent seasons, United are predicted to win 2-1, as Brentford's form has dipped under Keith Andrews, following a 3-1 loss to Fulham.

Chelsea host Brighton & Hove Albion, with former players Bryan Mbeumo and João Pedro posing threats. Chelsea may struggle without Cole Palmer, potentially starting a difficult period. Liverpool, unbeaten this season, take on a resilient Crystal Palace side that recently beat them on penalties; Liverpool will miss the suspended Hugo Ekitiké.

Leeds United, after a 3-1 win at Wolverhampton, welcome an impressive Bournemouth team to Elland Road. Newly-promoted Burnley are expected to adopt a defensive approach away at Manchester City. Nottingham Forest, following a 2-2 Europa League draw with Real Betis, face Sunderland, with new manager Ange Postecoglou showcasing his tactics at home. Wolverhampton Wanderers, winless in the league but boosted by a Carabao Cup win over Everton, meet Tottenham Hotspur, against whom they have a strong record, winning four of the last five encounters.